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RESEARCH OVERVIEW

Professor Forrest’s research focuses on using cutting-edge genomic techniques, in particular next generation DNA sequencing and computational approaches (bioinformatics) to understand how cells work at a system level. He has extensive experience in next generation sequencing (NGS) and has published using a variety of platforms (Roche, SOLiD, Illumina and Helicos) and protocols (RNA-seq, CAGE, small RNA, ChIP-seq). The move to Perkins in 2015 is allowing him to translate his basic research on mammalian systems onto clinically relevant questions such as identification of novel cancer biomarkers and drug targets.

Professor Alistair Forrest

Professor Alistair Forrest

Systems Biology and Genomics (Associate Director - Scientific Strategy)

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FANTOM5, WINNER 2016 Eureka Prize for Excellence in International Scientific Collaboration

LATEST NEWS

image shows ovarian cancer cells from various patients in various colours to show tumour elements

“Google map” of ovarian tumours reveals cancer cells control who gets into their neighbourhood

Perth researchers find some ovarian cancer cells appear to tell immune system to stay away. “Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones” published in…

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Predicting immunotherapy effectiveness in late-stage liver cancer

Blood test could hold key to identifying who will respond to immunotherapy after researchers discover biomarkers in liver cancer tissue. Liver cancer researchers at the Harry Perkins Institute of Medical…

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World melanoma expert exposes sailor’s skin cancer risk

Perth based cancer researcher Professor Jonas Nilsson regularly sees in his laboratory just how damaging sun exposure is to our skin as he investigates ways to treat melanoma, the most…

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