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RESEARCH OVERVIEW

Professor Forrest’s research focuses on using cutting-edge genomic techniques, in particular next generation DNA sequencing and computational approaches (bioinformatics) to understand how cells work at a system level. He has extensive experience in next generation sequencing (NGS) and has published using a variety of platforms (Roche, SOLiD, Illumina and Helicos) and protocols (RNA-seq, CAGE, small RNA, ChIP-seq). The move to Perkins in 2015 is allowing him to translate his basic research on mammalian systems onto clinically relevant questions such as identification of novel cancer biomarkers and drug targets.

Professor Alistair Forrest

Professor Alistair Forrest

Systems Biology and Genomics (Associate Director Scientific)

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FANTOM5, WINNER 2016 Eureka Prize for Excellence in International Scientific Collaboration

LATEST NEWS

Lowering cancer drug dose could open tumours to immunotherapy

Groundbreaking research undertaken at the Harry Perkins Institute of Medical Research in Perth has shown that administering anti-cancer drugs at a hundred-fold lower dose than standard protocols could improve the…

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1000 walkers raise over $1.45m for women’s cancer research

Taking steps to reduce the devastating impact of cancer on women. Fast Facts On average 69,000 new cases of cancer are diagnosed in Australian women each year. One in two…

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image shows ovarian cancer cells from various patients in various colours to show tumour elements

“Google map” of ovarian tumours reveals cancer cells control who gets into their neighbourhood

Perth researchers find some ovarian cancer cells appear to tell immune system to stay away. “Spatial transcriptomics reveals discrete tumour microenvironments and autocrine loops within ovarian cancer subclones” published in…

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