Chromatin and Ageing

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Home » Research » Labs » Genome Biology and Genetic Diseases Program » Chromatin and Ageing – Research Project

Home > Research > Labs > Genome Biology and Genetic Diseases Program > CHROMATIN AND AGEING

Research Projects

The Chromatin and Ageing Laboratory has recently been established. Research will focus on these areas:

Decoding epigenetic landscape of spatial ageing across organs and tissues.
From a drop of blood—longitudinal analysis of epigenetics in human peripheral blood cells.
Integrated analysis of functional ageing biomarkers in humans and different model organisms.
Development of new computational approaches for 3-dimensional analysis of chromatin structure and organisation.
Epigenetics of everything—biodiversity of Western Australia’s flora and fauna.

CURRENT STUDENT PROJECTS

Student Project

How do we age as single cells? Investigating spatial and temporal trajectories of epigenetic and biological age in single cells using microscopic imaging.

Student Project

How do we age as single cells? Investigating spatial and temporal trajectories of epigenetic and biological age in single cells using microscopic imaging.

Project Outline

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Chief supervisor
Professor Alexey V. Terskikh

Start date
Enquire now

Student Project

Cell heterogeneity during ageing (and rejuvenation). Does the 2nd law of thermodynamics apply to epigenetic information in single cells?

Student Project

Cell heterogeneity during ageing (and rejuvenation). Does the 2nd law of thermodynamics apply to epigenetic information in single cells?

Project Outline

Expand Close

Chief supervisor
Professor Alexey V. Terskikh

Start date
Enquire now

Student Project

Reprogramming vs transplantation induced rejuvenation: defining cell type-specific rejuvenation trajectories in different organs and tissues

Student Project

Reprogramming vs transplantation induced rejuvenation: defining cell type-specific rejuvenation trajectories in different organs and tissues

Project Outline

Expand Close

Chief supervisor
Professor Alexey V. Terskikh

Start date
Enquire now

Student Project

Accelerating the pace: defining and manipulating epigenetic trajectories of human neuronal maturation at the single-cell level.

Student Project

Accelerating the pace: defining and manipulating epigenetic trajectories of human neuronal maturation at the single-cell level.

Project Outline

Expand Close

Chief supervisor
Professor Alexey V. Terskikh

Other supervisor
Joint project with Prof Ryan Lister

Start date
Enquire now

Student Project

Best of both worlds: connecting microscopic imaging and deep sequencing to understand human brain cell ageing.

Student Project

Best of both worlds: connecting microscopic imaging and deep sequencing to understand human brain cell ageing.

Project Outline

Expand Close

Chief supervisor
Professor Alexey V. Terskikh

Other supervisor
Joint project with Prof Ryan Lister

Start date
Enquire now

Important information

All donations of $2 and over are tax deductible in Australia.

Perkins is registered with the Australian Taxation Office as a Deductible Gift Recipient (DGR): Charitable Fundraising Authority No DGR CC20761

The Harry Perkins Institute of Medical Research recognises Australia’s first healers and scientists, the Aboriginal and Torres Strait Islander peoples. We acknowledge the Whadjuk people of the Noongar nation, the Traditional Custodians of the lands where we live and work, and pay respects to their elders past and present.

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Research Projects

CURRENT STUDENT PROJECTS

Student Project

How do we age as single cells? Investigating spatial and temporal trajectories of epigenetic and biological age in single cells using microscopic imaging.

Student Project

How do we age as single cells? Investigating spatial and temporal trajectories of epigenetic and biological age in single cells using microscopic imaging.

Student Project

Cell heterogeneity during ageing (and rejuvenation). Does the 2nd law of thermodynamics apply to epigenetic information in single cells?

Student Project

Cell heterogeneity during ageing (and rejuvenation). Does the 2nd law of thermodynamics apply to epigenetic information in single cells?

Student Project

Reprogramming vs transplantation induced rejuvenation: defining cell type-specific rejuvenation trajectories in different organs and tissues

Student Project

Reprogramming vs transplantation induced rejuvenation: defining cell type-specific rejuvenation trajectories in different organs and tissues

Student Project

Accelerating the pace: defining and manipulating epigenetic trajectories of human neuronal maturation at the single-cell level.

Student Project

Accelerating the pace: defining and manipulating epigenetic trajectories of human neuronal maturation at the single-cell level.

Student Project

Best of both worlds: connecting microscopic imaging and deep sequencing to understand human brain cell ageing.

Student Project

Best of both worlds: connecting microscopic imaging and deep sequencing to understand human brain cell ageing.

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