Home  >  Research  >  Labs  >  Cancer Program  >  IRON METABOLISM LABORATORY

RESEARCH OVERVIEW

The Iron Metabolism Laboratory investigates the molecular mechanisms in normal iron metabolism and in the development of iron overload disorder hereditary haemochromatosis. We use transgenic murine models of iron overload and tumor cell lines to investigate cellular iron transport using radiolabelled tracers and expression of iron transporters and regulators of iron homeostasis. We have expertise in the area of molecular and cellular biology of iron including cell isolation and culture, iron transport, gene and protein expression, gene knockdown and immunohistochemistry. Our experience in these areas should be useful for participants in the ARC Metals in Medicine Network for the testing or screening of metals or metal complexes in biological systems.

LATEST NEWS

Dr Ankur Sharma in front of MRI image at Harry Perkins Institute of Medical Research

New liver cancer blood test gets $2.5m research funding boost

Predicting relapse for one of the world's deadliest cancers. Perth cancer researchers are on track to improve the outcomes of patients with the most common type of primary liver cancer. Hepatocellular carcinoma (HCC) is one of the most aggressive cancer types. Patients typically suffer a high rate of treatment failures.…

Read More
people in lab coats inside a cancer laboratory

ACRF Centre for Advanced Cancer Genomics opens in Perth

Latest technology analyses WA cancer patient tumours. The Australian Cancer Research Foundation (ACRF) Centre for Advanced Cancer Genomics, housing the next generation DNA sequencing technology, was opened today at the Harry Perkins Institute of Medical Research by the Federal Member for Curtin, Ms Kate Chaney. ACRF CEO, Kerry Strydom, in…

Read More

Connecting scientists and donors a winning mix

Harry Perkins Institute wins 2023 Fundraising Team of the Year In the midst of the Golden Globes and the Oscars season, a small team in Perth who support medical research has won three sought-after fundraising gongs, including Australia’s 2023 Fundraising Team of the Year. The team from the Harry Perkins…

Read More

I'M LOOKING FOR

RESEARCH PROJECTS

TEAM MEMBERS

PUBLICATIONS