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RESEARCH OVERVIEW

The Iron Metabolism Laboratory investigates the molecular mechanisms in normal iron metabolism and in the development of iron overload disorder hereditary haemochromatosis. We use transgenic murine models of iron overload and tumor cell lines to investigate cellular iron transport using radiolabelled tracers and expression of iron transporters and regulators of iron homeostasis. We have expertise in the area of molecular and cellular biology of iron including cell isolation and culture, iron transport, gene and protein expression, gene knockdown and immunohistochemistry. Our experience in these areas should be useful for participants in the ARC Metals in Medicine Network for the testing or screening of metals or metal complexes in biological systems.

LATEST NEWS

New Board members for Harry Perkins Institute

Brightwater Care Group Ltd immediate past CEO Jennifer Lawrence and long term BGC (Australia) Pty Ltd General Counsel, Belinda Murray have joined the Harry Perkins Institute of Medical Research Board commencing in June 2022. Both Non-Executive Directors have extensive experience in senior executive roles. Ms Lawrence recently completed six years…

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Near miss reaps rewards

The search for a cure to a disease that usually results in death before the age of one has caught the eye of a West Australian government program that supports outstanding local research. The disease is severe and debilitating. It causes profound muscle weakness and for parents the inevitable decline…

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Perkins recognised with $1.77m in WA’s Research Excellence Awards

Hard to treat cancers and rare disease gene discovery just some of the research supported by WA awards                                                                                        The Harry Perkins Institute of Medical Research received eight grants ranging from $110,000 to $340,000 in the WA Research Excellence Awards (REA) 2022 program. The grants are part of the…

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