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RESEARCH OVERVIEW

The Iron Metabolism Laboratory investigates the molecular mechanisms in normal iron metabolism and in the development of iron overload disorder hereditary haemochromatosis. We use transgenic murine models of iron overload and tumor cell lines to investigate cellular iron transport using radiolabelled tracers and expression of iron transporters and regulators of iron homeostasis. We have expertise in the area of molecular and cellular biology of iron including cell isolation and culture, iron transport, gene and protein expression, gene knockdown and immunohistochemistry. Our experience in these areas should be useful for participants in the ARC Metals in Medicine Network for the testing or screening of metals or metal complexes in biological systems.

LATEST NEWS

Why walk 35kms when you could walk 70?

Breast cancer survivor pushes herself to say thank you Four years clear of cancer, Connie Nicoletti-Lewins is committed to supporting the people who work to solve cancer’s mysteries and develop new treatments. Inspired by Perth’s annual Walk for Women’s Cancer that raises funds for cancer researchers at the Harry Perkins…

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Bioinformatics and high-performance computing evolution lead to better treatments for major diseases

It’s time to talk about bioinformatics and its influence on high-performance computing (HPC) as well as the importance of data analysis and interpretation in medical research. As part of Data Science Week events, 10-14 May, Perkins' bioinformatician Dr Elena Denisenko will join Dr Stuart Midgely, DUG CIO, physicist and high-performance…

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Moorditj Mob walking to support cancer research

Indigenous medical scientist Danielle Headland is choosing to honour her late mother by supporting Perth’s Walk for Women’s Cancer to help cancer researchers find new treatments and solve the mysteries of the disease that claimed her mother’s life. Danielle’s mother succumbed to uterine cancer in 2013, two years after diagnosis.…

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