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The Iron Metabolism Laboratory investigates the molecular mechanisms in normal iron metabolism and in the development of iron overload disorder hereditary haemochromatosis. We use transgenic murine models of iron overload and tumor cell lines to investigate cellular iron transport using radiolabelled tracers and expression of iron transporters and regulators of iron homeostasis. We have expertise in the area of molecular and cellular biology of iron including cell isolation and culture, iron transport, gene and protein expression, gene knockdown and immunohistochemistry. Our experience in these areas should be useful for participants in the ARC Metals in Medicine Network for the testing or screening of metals or metal complexes in biological systems.


AI to help WA researchers get to the heart of Australia’s #1 killer

Transforming heart care—WA researchers secure $2.99M grant for AI-driven health digitisation WA Researchers led by Professor Girish Dwivedi from the Harry Perkins Institute of Medical Research and The University of Western Australia (UWA) will establish a national database of Coronary Computed Tomography Angiography (CCTA) images to train an artificial intelligence…

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Swim for Your Life and Make a Splash for Medical Research

Perth’s Harry Perkins Institute of Medical Research announces a new fundraising challenge event to raise money to fight the world’s toughest diseases. Perth’s Harry Perkins Institute of Medical Research is excited to announce a challenging new fundraising event, the Perkins Plunge, a thrilling 12-hour overnight relay swim set to take…

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Image of flowering Arabidopsis thaliana

‘Smart’ Plants for Space Travel

Researchers from Harry Perkins Institute of Medical Research and the University of Western Australia have developed synthetic genetic circuits that can turn plant genes on or off based on the environment. The botanical breakthrough could lead to the creation of plants that can be customised to support space exploration. Imagine…

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