The Onco-Fetal Ecosystem Laboratory focuses on the triquetra of early development, regeneration, and cancer. We are interested in understanding the developmental origin of cancer by uncovering the similarities between embryogenesis and tumor development. In close association with our clinical collaborators, we study how tumors co-evolve with their microenvironment, especially in the context of tumor initiation and resistance to immunotherapy. To address these questions, we combine single-cell genomics, spatial transcriptomics, and machine learning approaches. We are expanding our collaborations to integrate experimental, computational, and clinical knowledge to exhume the ‘seeds’ of cancer development.
More detailed information on the Onco-Fetal Laboratory can be found at Sharma Lab’s dedicated page: http://www.oncofetal.com/
All donations of $2 and over are tax deductible in Australia.
Perkins is registered with the Australian Taxation Office as a Deductible Gift Recipient (DGR): Charitable Fundraising Authority No DGR CC20761
We acknowledge the Whadjuk people of the Nyoongar nation, the traditional owners of the lands where our offices are located and pay respects to their elders, past, present and emerging.
