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RESEARCH OVERVIEW

The Onco-Fetal Ecosystem Laboratory focuses on the triquetra of early development, regeneration, and cancer. We are interested in understanding the developmental origin of cancer by uncovering the similarities between embryogenesis and tumor development. In close association with our clinical collaborators, we study how tumors co-evolve with their microenvironment, especially in the context of tumor initiation and resistance to immunotherapy. To address these questions, we combine single-cell genomics, spatial transcriptomics, and machine learning approaches. We are expanding our collaborations to integrate experimental, computational, and clinical knowledge to exhume the ‘seeds’ of cancer development.

More detailed information on the Onco-Fetal Laboratory can be found at Sharma Lab’s dedicated page: http://www.oncofetal.com/

Dr Ankur Sharma

Dr Ankur Sharma

Onco-Fetal Ecosystem

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LATEST NEWS

New discovery for treatment of primary liver cancer shows promise

A study using preclinical models has discovered a drug combination with the potential to treat one of the most fatal and globally widespread cancers, a type of primary liver cancer…

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Perkins researchers Prof Jonas Nilsson and Dr Peter Lau at lab bench with equipment

WA melanoma research featured at global Oncology congress

Breakthrough research from the Harry Perkins Institute of Medical Research that explores possible new treatments for melanoma will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting.…

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Dr Ankur Sharma in front of MRI image at Harry Perkins Institute of Medical Research

New liver cancer blood test gets $2.5m research funding boost

Predicting relapse for one of the world's deadliest cancers. Perth cancer researchers are on track to improve the outcomes of patients with the most common type of primary liver cancer.…

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