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RESEARCH OVERVIEW

The Onco-Fetal Ecosystem Laboratory focuses on the triquetra of early development, regeneration, and cancer. We are interested in understanding the developmental origin of cancer by uncovering the similarities between embryogenesis and tumor development. In close association with our clinical collaborators, we study how tumors co-evolve with their microenvironment, especially in the context of tumor initiation and resistance to immunotherapy. To address these questions, we combine single-cell genomics, spatial transcriptomics, and machine learning approaches. We are expanding our collaborations to integrate experimental, computational, and clinical knowledge to exhume the ‘seeds’ of cancer development.

More detailed information on the Onco-Fetal Laboratory can be found at Sharma Lab’s dedicated page: http://www.oncofetal.com/

Dr Ankur Sharma

Dr Ankur Sharma

Onco-Fetal Ecosystem

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LATEST NEWS

Perkins secures biobanking grants to answer important questions in future research

The McGowan Government recently announced that the Harry Perkins Institute will receive two of the 16 grants totalling more than $1.5 million to support Western Australian biobanks. Congratulations to both…

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NHMRC funding for DEFINER to identify “the right drug for the right patient” in liver cancer

The Harry Perkins Institute's Oncofetal Ecosystem Laboratory, established early in 2021, has received its first NHMRC Ideas Grant in the most recent grants round. This collaborative project run by the…

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West Australians making a difference to cancer

How riders are making a difference in battle against cancer OpEd Opinion piece, page 42, The West Australian: 21 October 2021, by Professor Peter Leedman AO For the tenth year I…

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