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OVERVIEW

The Perkins Monoclonal Antibody Facility produces pure, high quality antibodies needed for medical or research purposes to researchers and commercial clients. Researchers and biotechnology companies have access to the custom-made antibodies necessary to develop new products such as diagnostic tools. Monoclonal antibodies have been used to successfully treat breast cancer, lymphoma, rheumatoid arthritis, asthma, leukaemia and in transplants to minimise the chances of organ rejection.

Our services range from production of antisera to manufacture of gram amounts of pure monoclonal antibodies. Our specialty is in the production of custom monoclonal antibodies made with our high efficiency proprietary technology. We are one of the only suppliers with a strong track record in producing MAb to novel antigens that are particularly challenging.

The facility is managed by Kathleen Davern. Kathy has many years of experience in all aspects of monoclonal antibody production and has built on these strengths to expand both national and international capabilities.

National and international researchers, clinicians and commercial groups have expressed their satisfaction with the value and efficiency of our services.

We use Perkins own super-antibody producing “Southern Cross” strain SC 073 routinely for superior monoclonal antibody production.

SERVICES

The Facility provides a wide range of antibody-related products and services, including:

  • High efficiency custom production of monoclonal antibodies (MAb) using “Southern Cross”
  • Archive storage of cell lines
  • Polyclonal antibody production
  • Peptide synthesis and conjugation
  • In vitro production of MAbs in Bioreactors
  • Purification, conjugation and fragmentation of MAbs
  • Immunological assays
  • Humanisation of monoclonal antibodies
  • Phage display analysis
  • Nanobody production from Perkins camelid library

CAPABILITIES

  • Absolute client confidentiality
  • Perkins ethics committee compliance
  • Large repository of valuable hybridoma lines and antibodies
  • University of Western Australia ethics approval
  • Production of MAb at Good Laboratory Practice level
  • Production of up to 1000 mg per run
  • State-of-the-art equipment for MAb production
  • Ability and support to expand the provision of products and services

Get in touch

Kathleen Davern
Monoclonal Antibody Facility
T. +61 8 6151 0739
E. [email protected]

The Harry Perkins Institute of Medical Research is as signatory to the Australian and New Zealand Council for the Care of Animals in Research and Teaching’s (ANZCCART) Animals in Research Openness Agreement.