Jordan is a PhD student in the Disease Models and Therapies Team within the Preventive Genetics group. He has a Bachelor of Biomedical Science in Physiology and Chemistry. He completed Honours in Physiology in 2021, investigating the role of paraspeckles in breast tumour growth and metastasis. He joined Perkins in 2022 as a research assistant within the Liver Cancer Collaborative, processing patient blood samples for the Biobank platform and performing single cell RNA-seq experiments for the Omics platform.
Jordan’s PhD will focus on RYR1-related myopathies, which affect around 90,000 individuals worldwide and are the most common class of congenital myopathy. His research aims to model RYR1-related myopathies using patient cells which have been converted into induced pluripotent stem cells, then differentiated into skeletal muscle cells. These models will enable detailed characterisation of RYR1-related myopathies at a cellular level, leading to a better understanding of the underlying disease mechanisms. Jordan also aims to use these models to develop new genetic treatments for RYR1-related myopathy, which target the underlying molecular defects that cause disease.