Professor Daniel Fatovich

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Professor Daniel Fatovich

Clinical science division

Professor Daniel Fatovich

Clinical science division


Professor Daniel Fatovich is a senior emergency physician and clinical researcher at Royal Perth Hospital Emergency Department, one of the busiest Emergency Departments in Australasia. His over 25 years of experience in the design and conduct of clinical trials in Emergency Medicine has a focus on patient-oriented outcomes. The breadth of his research includes national collaborative clinical trials, which has led to a network of like-minded researchers across Australia and New Zealand.
Prof Fatovich is widely published in all aspects of emergency medicine research, and is regularly invited to speak at state, national and international meetings. He is also heavily involved in research with the Australasian College for Emergency Medicine (ACEM) and is an executive member of the ACEM Clinical Trials Network. He has regularly won College research awards.
As Professor of Emergency Medicine, University of Western Australia, Prof Fatovich teaches critical appraisal of the emergency medicine literature to advanced trainees in emergency medicine. On the international scene, he is a member of the List of Industry Independent Experts (invitation only), listed on HealthNewsReview (, The Lown Institute.
In 2016, one of his papers was selected by Emergency Medical Abstracts as the basis for an author interview, and this paper was chosen as one of their papers of the year.
In 2018 he was appointed Director of Research for Royal Perth Hospital. The appointment includes chairing the Scientific Advisory Committee of the Royal Perth Hospital Medical Research Foundation.


1983 MBBS – Bachelor of Medicine Bachelor of Surgery, University of Western Australia, Australia
1990 FACEM – Fellowship of the Australasian College for Emergency Medicine
2012 PhD- University of Western Australia, Australia / Thesis: Major trauma in Western Australia and the effects of distance, time and remoteness on mortality.

Special Interests

  • Trauma – the early management of severe trauma, rural and remote trauma outcomes and trauma epidemiology; electrical injuries
  • The societal aspects of emergency medicine: access block, alcohol and illicit drug use, & mental health
  • Resuscitation, Pain, Sepsis, Neuroscience & Toxicology
  • The use of linked health data
  • Research methodology & bias

Major Grants Awarded

2016 NHMRC Project Grant APP1122792; 4-years (2017-2020) Briffa T, Cullen L, Chew D, Knuiman M, Fatovich D, Hickman P, Parsonage W, Nedkoff L, Sanfilippo F, Hillis G, Mitra B, Wilkes G, Schneider H, Rankin J, Karnon J, Scanlan S, Stapleton S, Mather V. Is highly-sensitive troponin testing advancing clinical practice, improving outcomes and cost-effective in the investigation and management of chest pain in the Emergency Department? $1,197,000.
 2016 NHMRC APP1116453 Cameron P, Finn J, Bernard S, Grantham H, Smith K, Fatovich D,Arendts G, Bray J, Stub D, Perkins G. Centre of Research Excellence in Prehospital Emergency Care. $2,499,626.
 2016 SHRAC Research Translation Project Hillis G, Alcock R, Spiro J, Fatovich D, Macdonald S, Schultz C, Briffa T, Geelhoed E. The Royal Perth evidence-based accelerated chest pain pathway implementation (RAPID) study. $242,858.
 2016 SHRAC Research Translation Project Williams T, Finn J,Arendts G, Fatovich D, McQuillan B, Perkins G, Hendrie D, Bailey P, Summers Q, Brink D. A randomised controlled trial of Continuous Positive Airway Pressure (CPAP) for the treatment of severe respiratory distress by ambulance paramedics in the pre-hospital setting. $97,345.
 2015 Queensland Emergency Medicine Research Foundation Keijzers G, Macdonald S, Kinnear F,Arendts G, Brown S, Fatovich D, Taylor D, Vlad I, McCutcheon D, Asha A. Restricted Fluid Resuscitation in Sepsis-associated Hypotension (REFRESH) Trial. $54,125.
2015 Neurotrauma Research program Fitzgerald L, Fatovich D, Pestell C. Identification of biomarkers that correlate with clinical features and outcomes followingconcussion. $38,925.
2015 SHRAC Research Translation Project. Stafford A, Fatovich D, Bynevelt M, Licari M, Reynolds J, Christmass M, Quigley A. Methamphetamine Addiction: Is Baclofen effective in suppressing methamphetamine cravings? Functional MRI patterns of brain activation in Baclofen vs placebo treated methamphetamine addicts. $251,904.
2014 NHMRC 2014 Partnership project grant APP1076949; Finn J, Jacobs I, Fatovich D, Smith K, Williams T, Hendrie D, O’Halloran K, Cameron P. Improving ambulance dispatch to time-critical emergencies. $482,723.
2012 Western Australia Department of Health, Targeted Research Fund. Jacobs I, Finn J, Fatovich D, Arendts G, Mountain D, Williams T, Gibson N, Sprivulis P, Celenza T. Evidence-based paramedic models of care to reduce unnecessary emergency department attendance. $370,000.
2011 NHMRC 2012 Partnership project grant APP 1029492 Forero R, Hillman K, Fatovich D, McCarthy S, Mountain D, Fitzgerald G, Richardson D, Sprivulis P, Middleton P. Validation and impact of the four hour rule in the emergency department: a large data linkage study. $687000, Western Australia Department of Health ($150000), Australasian College for Emergency Medicine ($100000), NSW Ministry of Health ($200000). Total grant monies $1,718,864.
2010 Neurotrauma Research Program, Western Australian Institute for Medical Research. Leukocyte cellsignalling after major head trauma: correlation with clinical outcomes. Brown S, Stone S, Webb S, Henry N, Rao S, Fatovich D,Arendts G. (2011: $105789).
2008 Royal Perth Hospital Medical Research Foundation (Infrastructure Grant). Establishing a Centre for Clinical Research in Emergency Medicine. 2009: $126,412, 2010: $66072. Brown SGA, Stone SF,Arendts G, Fatovich DM.
2007 Raine Priming Grant, Raine Medical Research Foundation. A study of trauma patients transferred from rural and remote Western Australia by the Royal Flying Doctor Service. $10,000.
2007 Royal Perth Hospital Medical Research Foundation. A screening MRI study to determine the prevalence of cerebral abnormalities in patients presenting with acute amphetamine intoxication. $10,000.
2006 Department of Health and Aging, Australian Government. Chlamydia Targeted Grants Program. $301,891. McCloskey J, Dykstra C, Flexman J, Fatovich DM.

Selected Publications

1. Fatovich DM. The inverted U curve and Emergency Medicine: Overdiagnosis and the law of unintended consequences. Emerg Med Australas 2016;28:480-482. [NCBI PubMed Entry]

2. Fatovich DM, Jacobs IG. 1995. A Randomised Controlled Trial of Oral Midazolam and Buffered Lidocaine for Suturing Lacerations in Children (the SLIC Trial). Annals of Emergency Medicine 25:209-214 (John Gilroy Potts Award). [NCBI PubMed Entry]

3. Fatovich DM, Prentice DA, Dobb GJ. 1997. Magnesium in Cardiac Arrest (the magic trial). Resuscitation 35:237-241. [NCBI PubMed Entry]

4. Fatovich DM, Dobb GJ, Clugston RA. 2004. A pilot randomised trial of thrombolysis in cardiac arrest (The TICA trial). Resuscitation 61:309-313. [NCBI PubMed Entry]

5. Fatovich DM, Jacobs IG. 2009. The relationship between remoteness and trauma deaths in Western Australia. The Journal of Trauma 67:910-4. [NCBI PubMed Entry]

6. Fatovich DM, McCoubrie DL, Song SJ, Rosen DM, Lawn ND, Daly FF. 2010. Brain abnormalities detected on magnetic resonance imaging of amphetamine users presenting to an emergency department: a pilot study. The Medical Journal of Australia 193(5):266-8. [NCBI PubMed Entry]

7. Lenzer J, Hoffman JR, Furberg CD, Ioannidis JP. Ensuring the integrity of clinical practice guidelines: a tool for protecting patients. BMJ 2013;347:f5535 [NCBI PubMed Entry]

8. Brown SG, Stone SF, Fatovich DM, Burrows SA, Holdgate A, Celenza A, Coulson A, Hartnett L, Nagree Y, Cotterell C, Isbister GK. Anaphylaxis: clinical patterns, mediator release and severity. J Allergy Clin Immunol 2013;132:1141-1149.e5. (John Gilroy Potts Award) [NCBI PubMed]

9. Isbister GK, Page CB, Buckley NA, Fatovich DM, Pascu O, Macdonald SP, Calver LA, Brown SG. Randomized controlled trial of intravenous antivenom versus placebo for Latrodectism: the second Redback antivenom evaluation (RAVE-II) study. Ann Emerg Med 2014;64:620-628.e2. (John Gilroy Potts Award) [NCBI PubMed Entry]

10. Egerton-Warburton D, Gosbell AD, Wadsworth A, Fatovich DM, Richardson DB. Survey of alcohol-related presentations to Australasian Emergency Departments. Med J Aust 2014;201: 584-587. (Ed Brentnall Award) [NCBI PubMed Entry]

11. Taylor D, Fatovich D, Finucci D, Furyk J, Jin S, Keijzers G, Macdonald S, Mitenko H, Richardson J, Ting J, Thom O, Ugoni A, Hughes J, Bost N, Ward M, Gibbs C, Macdonald E, Chalkley D. Best-practice pain management in the Emergency Department: a cluster-randomised controlled intervention trial. Emerg Med Australas 2015;27:549-557. [NCBI PubMed Entry]