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T-Test Calculator

Use your measurements to find out whether the difference you see is likely to be due to real variation or something more than chance.

🔬 Choose the comparison that matches your experiment. If you have several measurements that you want to compare with one expected or “no effect” value, choose the first option.

What are you comparing?

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My measurements vs an expected value

You have several measurements and want to compare them with one known or expected value.

Example: comparing measured zones of inhibition with the diameter of an antibiotic disk. One-sample t-test
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Two different groups

You have measurements from two separate groups and want to see whether they differ.

Example: comparing measurements from treated and untreated samples. Welch's t-test
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The same samples twice

You measured the same samples under two different conditions or at two different times.

Example: measuring the same samples before and after treatment. Paired t-test

Expected

Observed

Two-tailed p-value
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What does this mean?

Your t-value on the t-distribution

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