Gain a deeper understanding of how mutations can be identified through PCR, Gel Electrophoresis and Sequencing in interactive wet and dry lab activities.
In the dry lab, students will discuss the causes and effects of mutations, and how the process of PCR can help us gain greater insights into them.
Content includes
- Exploring different types, impacts, and causes of genetic mutations in human populations
- A brief revision of DNA replication and protein synthesis
- Considering germ-line mutations and their effect on the gene pool
- Using gene technologies in the lab (PCR and Gel Electrophoresis) to understand the incidence of disease within a family
In the lab, students work on a case-study family with a genetic disease. They identify the mutation using the techniques of PCR and Gel Electrophoresis.
Students then learn about DNA sequencing, and how it is used to find the cause of the genetic disease.
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