CellsDisease AreaEpigenetics and Genomics LaboratoryLabMolecular MedicineNews & EventsResearchResearch Area
Stem cell reprogramming mystery clarified by new findings
By Marlin Communications | Cells, Disease Area, Epigenetics and Genomics Laboratory, Lab, Molecular Medicine, News & Events, Research, Research AreaIn a study, published in Cell Stem Cell, researchers from the University of Western Australia, the Harry Perkins Institute of Medical Research, and Monash University describe key drivers of the process…
Cardiovascular DiseaseDisease AreaLabMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch Area
Faulty gene linked to obesity in adults
By Marlin Communications | Cardiovascular Disease, Disease Area, Lab, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research AreaThe study, published in Science Advances, found that reduced function of a gene that impacts the breakdown of fats resulted in adult-onset obesity and fatty liver. Head of the Mitochondrial…
CancerChronic Kidney DiseaseDisease AreaLabMolecular Endocrinology and PharmacologyMolecular MedicineNews & EventsResearchResearch Area
New way to examine how medicines act on cells
By Marlin Communications | Cancer, Chronic Kidney Disease, Disease Area, Lab, Molecular Endocrinology and Pharmacology, Molecular Medicine, News & Events, Research, Research AreaUsing a genome editing technique called CRISPR/Cas9, the researchers attached a super-bright glowing molecule, derived from deep sea shrimp, to specific molecules important for signalling in cancer cells, ‘receptors’. Receptors…
LabMolecular MedicineNews & EventsRare Disease Genetics and Functional GenomicsResearchResearch Area
Sudden infant cardiac death explained by gene mutation
By Marlin Communications | Lab, Molecular Medicine, News & Events, Rare Disease Genetics and Functional Genomics, Research, Research AreaLast year the Perkins Neurogenetic Diseases Laboratory received DNA from a family in Scotland whose four-month-old baby had tragically suffered a cardiac arrest and died. With the family’s permission, their doctor sent…
Disease AreaHeartLabMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch AreaSynthetic Biology and Drug Discovery
Perkins researchers find essential gene for healthy hearts
By Marlin Communications | Disease Area, Heart, Lab, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research Area, Synthetic Biology and Drug DiscoveryProfessor Aleksandra Filipovska and her team from the Perkins Mitochondrial Medicine and Biology Laboratory in collaboration with Professor Oliver Rackham and Professor Nils Göran Larsson and his team from the Max Planck Institute for Biology…
Disease AreaGenesLabMolecular MedicineMusclesNews & EventsRare Disease Genetics and Functional GenomicsResearchResearch Area
Perkins researchers decipher world-first muscle disorder cases
By Marlin Communications | Disease Area, Genes, Lab, Molecular Medicine, Muscles, News & Events, Rare Disease Genetics and Functional Genomics, Research, Research AreaDuring their investigation the multi-national team of researchers studied a muscle protein that is strongly influenced by calcium. The protein, known as tropomyosin-3 (TPM3), is vital for skeletal muscle development…
Disease AreaLabMitochondrial diseaseMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch Area
Cause of mitochondrial dysfunction discovered by Perkins researchers
By Marlin Communications | Disease Area, Lab, Mitochondrial disease, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research AreaThe disease, known as Leigh Syndrome, has previously been linked to a genetic mutation, but Perkins researchers were able to determine how the mutation led to mitochondrial dysfunction. Mitochondria are…
Epigenetics and Genomics LaboratoryLabMolecular MedicineNews & EventsResearchResearch Area
Groundbreaking discovery on the process of vertebrate development
By Marlin Communications | Epigenetics and Genomics Laboratory, Lab, Molecular Medicine, News & Events, Research, Research AreaProfessor Ryan Lister and Dr Ozren Bogdanovic from the Perkins Epigenetics and Genomics Laboratory led the study, which has been published in in the prestigious journal Nature Genetics. Their work is focused on…
