Cancer and Cell BiologyDisease AreaNews & EventsResearchResearch AreaTumours
New drug to supercharge immune cells in the fight against cancer
By Marlin Communications | Cancer and Cell Biology, Disease Area, News & Events, Research, Research Area, TumoursMany tumours can become resistant to the body’s immune system by creating a barrier of tangled blood vessels that feed the tumour while locking out immune cells that would attack…
Cardiovascular DiseaseDisease AreaLabMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch Area
Faulty gene linked to obesity in adults
By Marlin Communications | Cardiovascular Disease, Disease Area, Lab, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research AreaThe study, published in Science Advances, found that reduced function of a gene that impacts the breakdown of fats resulted in adult-onset obesity and fatty liver. Head of the Mitochondrial…
CancerChronic Kidney DiseaseDisease AreaLabMolecular Endocrinology and PharmacologyMolecular MedicineNews & EventsResearchResearch Area
New way to examine how medicines act on cells
By Marlin Communications | Cancer, Chronic Kidney Disease, Disease Area, Lab, Molecular Endocrinology and Pharmacology, Molecular Medicine, News & Events, Research, Research AreaUsing a genome editing technique called CRISPR/Cas9, the researchers attached a super-bright glowing molecule, derived from deep sea shrimp, to specific molecules important for signalling in cancer cells, ‘receptors’. Receptors…
Disease AreaGenetic DiseaseLabNews & EventsRare Disease Genetics and Functional GenomicsResearch
Better diagnosis thanks to advanced new technology
By Marlin Communications | Disease Area, Genetic Disease, Lab, News & Events, Rare Disease Genetics and Functional Genomics, ResearchWorking with international research groups, including the Broad Institute in Boston, the teams used a new technology called RNA-sequencing that interprets the ‘messages’ from genes, rather than observing the genes…
CancerCancer and Cell BiologyDisease AreaGenesLabNews & EventsResearchResearch AreaSystems Biology and Genomics
Ground-breaking new study doubles the estimate of our functional genes
By Marlin Communications | Cancer, Cancer and Cell Biology, Disease Area, Genes, Lab, News & Events, Research, Research Area, Systems Biology and GenomicsThe findings, published in Nature, were the latest work of the FANTOM5 consortium, a group of researchers from Japan and Australia led by Professor Alistair Forrest from the Perkins and The University of…
Breast CancerCancer and Cell BiologyCancer EpigeneticsDisease AreaLabNews & EventsResearchResearch Area
New method to fight hard to treat breast cancers
By Marlin Communications | Breast Cancer, Cancer and Cell Biology, Cancer Epigenetics, Disease Area, Lab, News & Events, Research, Research AreaThe research led by Perkins researcher Dr Anabel Sorolla involves the use of nanoparticles to deliver a series of anti-cancer agents directly to the tumour. The study focused on triple…
LabMolecular MedicineNews & EventsRare Disease Genetics and Functional GenomicsResearchResearch Area
Sudden infant cardiac death explained by gene mutation
By Marlin Communications | Lab, Molecular Medicine, News & Events, Rare Disease Genetics and Functional Genomics, Research, Research AreaLast year the Perkins Neurogenetic Diseases Laboratory received DNA from a family in Scotland whose four-month-old baby had tragically suffered a cardiac arrest and died. With the family’s permission, their doctor sent…
Cancer and Cell BiologyCancer EpigeneticsDisease AreaLabNews & EventsResearchResearch AreaTumours
Perkins researchers turn on cancer killing genes
By Marlin Communications | Cancer and Cell Biology, Cancer Epigenetics, Disease Area, Lab, News & Events, Research, Research Area, TumoursDr Benjamin Garcia Bloj, along with his labmates from the Perkins Cancer Epigenetics Laboratory headed by Associate Professor Pilar Blancafort, used a gene-editing technology called CRISPR to ‘wake up’ key tumour suppressors to…
