Breast CancerCancer and Cell BiologyCancer EpigeneticsDisease AreaLabNews & EventsResearchResearch Area
New method to fight hard to treat breast cancers
By leafcutter_admin | Breast Cancer, Cancer and Cell Biology, Cancer Epigenetics, Disease Area, Lab, News & Events, Research, Research AreaThe research led by Perkins researcher Dr Anabel Sorolla involves the use of nanoparticles to deliver a series of anti-cancer agents directly to the tumour. The study focused on triple…
LabMolecular MedicineNeurogenetic DiseasesNews & EventsResearchResearch Area
Sudden infant cardiac death explained by gene mutation
By leafcutter_admin | Lab, Molecular Medicine, Neurogenetic Diseases, News & Events, Research, Research AreaLast year the Perkins Neurogenetic Diseases Laboratory received DNA from a family in Scotland whose four-month-old baby had tragically suffered a cardiac arrest and died. With the family’s permission, their doctor sent…
Cancer and Cell BiologyCancer EpigeneticsDisease AreaLabNews & EventsResearchResearch AreaTumours
Perkins researchers turn on cancer killing genes
By leafcutter_admin | Cancer and Cell Biology, Cancer Epigenetics, Disease Area, Lab, News & Events, Research, Research Area, TumoursDr Benjamin Garcia Bloj, along with his labmates from the Perkins Cancer Epigenetics Laboratory headed by Associate Professor Pilar Blancafort, used a gene-editing technology called CRISPR to ‘wake up’ key tumour suppressors to…
Disease AreaHeartLabMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch AreaSynthetic Biology and Drug Discovery
Perkins researchers find essential gene for healthy hearts
By leafcutter_admin | Disease Area, Heart, Lab, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research Area, Synthetic Biology and Drug DiscoveryProfessor Aleksandra Filipovska and her team from the Perkins Mitochondrial Medicine and Biology Laboratory in collaboration with Professor Oliver Rackham and Professor Nils Göran Larsson and his team from the Max Planck Institute for Biology…
Disease AreaGenesLabMolecular MedicineMusclesNeurogenetic DiseasesNews & EventsResearchResearch Area
Perkins researchers decipher world-first muscle disorder cases
By leafcutter_admin | Disease Area, Genes, Lab, Molecular Medicine, Muscles, Neurogenetic Diseases, News & Events, Research, Research AreaDuring their investigation the multi-national team of researchers studied a muscle protein that is strongly influenced by calcium. The protein, known as tropomyosin-3 (TPM3), is vital for skeletal muscle development…
Disease AreaLabMitochondrial diseaseMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch Area
Cause of mitochondrial dysfunction discovered by Perkins researchers
By leafcutter_admin | Disease Area, Lab, Mitochondrial disease, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research AreaThe disease, known as Leigh Syndrome, has previously been linked to a genetic mutation, but Perkins researchers were able to determine how the mutation led to mitochondrial dysfunction. Mitochondria are…
Epigenetics and Genomics LaboratoryLabMolecular MedicineNews & EventsResearchResearch Area
Groundbreaking discovery on the process of vertebrate development
By leafcutter_admin | Epigenetics and Genomics Laboratory, Lab, Molecular Medicine, News & Events, Research, Research AreaProfessor Ryan Lister and Dr Ozren Bogdanovic from the Perkins Epigenetics and Genomics Laboratory led the study, which has been published in in the prestigious journal Nature Genetics. Their work is focused on…
Clinical ScienceDiabetesDiabetes ResearchDisease AreaLabNews & EventsResearchResearch Area
Search for a diet to protect against Diabetes
By leafcutter_admin | Clinical Science, Diabetes, Diabetes Research, Disease Area, Lab, News & Events, Research, Research AreaProfessor Grant Morahan, who heads the Centre for Diabetes Research at the Harry Perkins Institute of Medical Research, said that the study aimed to help people choose the ideal diet…
