Cardiovascular DiseaseDisease AreaLabMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch Area
Faulty gene linked to obesity in adults
By Marlin Communications | Cardiovascular Disease, Disease Area, Lab, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research AreaThe study, published in Science Advances, found that reduced function of a gene that impacts the breakdown of fats resulted in adult-onset obesity and fatty liver. Head of the Mitochondrial…
CancerChronic Kidney DiseaseDisease AreaLabMolecular Endocrinology and PharmacologyMolecular MedicineNews & EventsResearchResearch Area
New way to examine how medicines act on cells
By Marlin Communications | Cancer, Chronic Kidney Disease, Disease Area, Lab, Molecular Endocrinology and Pharmacology, Molecular Medicine, News & Events, Research, Research AreaUsing a genome editing technique called CRISPR/Cas9, the researchers attached a super-bright glowing molecule, derived from deep sea shrimp, to specific molecules important for signalling in cancer cells, ‘receptors’. Receptors…
Disease AreaGenetic DiseaseLabNews & EventsRare Disease Genetics and Functional GenomicsResearch
Better diagnosis thanks to advanced new technology
By Marlin Communications | Disease Area, Genetic Disease, Lab, News & Events, Rare Disease Genetics and Functional Genomics, ResearchWorking with international research groups, including the Broad Institute in Boston, the teams used a new technology called RNA-sequencing that interprets the ‘messages’ from genes, rather than observing the genes…
CancerCancer and Cell BiologyDisease AreaGenesLabNews & EventsResearchResearch AreaSystems Biology and Genomics
Ground-breaking new study doubles the estimate of our functional genes
By Marlin Communications | Cancer, Cancer and Cell Biology, Disease Area, Genes, Lab, News & Events, Research, Research Area, Systems Biology and GenomicsThe findings, published in Nature, were the latest work of the FANTOM5 consortium, a group of researchers from Japan and Australia led by Professor Alistair Forrest from the Perkins and The University of…
Breast CancerCancer and Cell BiologyCancer EpigeneticsDisease AreaLabNews & EventsResearchResearch Area
New method to fight hard to treat breast cancers
By Marlin Communications | Breast Cancer, Cancer and Cell Biology, Cancer Epigenetics, Disease Area, Lab, News & Events, Research, Research AreaThe research led by Perkins researcher Dr Anabel Sorolla involves the use of nanoparticles to deliver a series of anti-cancer agents directly to the tumour. The study focused on triple…
Cancer and Cell BiologyCancer EpigeneticsDisease AreaLabNews & EventsResearchResearch AreaTumours
Perkins researchers turn on cancer killing genes
By Marlin Communications | Cancer and Cell Biology, Cancer Epigenetics, Disease Area, Lab, News & Events, Research, Research Area, TumoursDr Benjamin Garcia Bloj, along with his labmates from the Perkins Cancer Epigenetics Laboratory headed by Associate Professor Pilar Blancafort, used a gene-editing technology called CRISPR to ‘wake up’ key tumour suppressors to…
Disease AreaHeartLabMitochondrial Medicine and BiologyMolecular MedicineNews & EventsResearchResearch AreaSynthetic Biology and Drug Discovery
Perkins researchers find essential gene for healthy hearts
By Marlin Communications | Disease Area, Heart, Lab, Mitochondrial Medicine and Biology, Molecular Medicine, News & Events, Research, Research Area, Synthetic Biology and Drug DiscoveryProfessor Aleksandra Filipovska and her team from the Perkins Mitochondrial Medicine and Biology Laboratory in collaboration with Professor Oliver Rackham and Professor Nils Göran Larsson and his team from the Max Planck Institute for Biology…
Disease AreaGenesLabMolecular MedicineMusclesNews & EventsRare Disease Genetics and Functional GenomicsResearchResearch Area
Perkins researchers decipher world-first muscle disorder cases
By Marlin Communications | Disease Area, Genes, Lab, Molecular Medicine, Muscles, News & Events, Rare Disease Genetics and Functional Genomics, Research, Research AreaDuring their investigation the multi-national team of researchers studied a muscle protein that is strongly influenced by calcium. The protein, known as tropomyosin-3 (TPM3), is vital for skeletal muscle development…
