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SELECTED PUBLICATIONS

Mishra A, Lai GC, Yao LJ, Aung TT, Shental N, Maskowitz AR, Shepherdson E, Singh G, Pai R, Shanti A, Wong R, Lee A, Khyreim C, Dutertre CA, Chakarov S, Srinivasan K, Shadan N, Zhang X, Khalilnezhad S, Cottier F, Tan A, Low G, Chen P, Fan Y, Hor P, Lee A, Choolani M, Vermijlen D, Sharma A, Fuks G, Straussman R, Pavelka N, Malleret B, McGovern N, Albani S, Chan J, Ginhoux F. Microbial exposure during early human development primes fetal immune cells (In press Cell)

Seow JJW, Pai R, Mishra A, Shepherdson E, Lim TKH, Goh BKP, Chan JKY, Chow PKH, Ginhoux F, DasGupta R, Sharma A. “scRNA-seq reveals ACE2 and TMPRSS2 expression in TROP2+ Liver Progenitor Cells: Implications in COVID-19 associated Liver Dysfunction.” Frontiers in Medicine (2021)

Sharma A, Seow JJW, Dutertre CA, Pai R, Blériot C, Mishra A, Wong RMM, Singh GSN, Sudhagar S, Khalilnezhad S, Erdal S, Teo HM, Khalilnezhad A, Chakarov S, Lim TKH, Fui ACY, Chieh AKW, Chung CP, Bonney CK, Goh BKP, Chan JKY, Chow PKH, Ginhoux F, DasGupta R.”Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma.” Cell (2020)

Suphavilai C, Chia S, Sharma A, Tu L, Peres R, Mongia A, DasGupta R, Nagarajan N. “Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures.” bioRxiv (2020)

Seow JJW, Wong RMM, Pai R, Sharma A. “Single‐Cell RNA Sequencing for Precision Oncology: Current State-of-Art.” Journal of Indian Institute of Science (2020)

Ravasio A, Myaing MZ, Chia S, Arora A, Sathe A, Cao EY, Bertocchi C, Sharma A, Arasi B, Chung VY, Greene AC, Tan TZ, Chen Z, Ong HT, Iyer NG, Huang RYJ, DasGupta R, Groves JT, Viasnoff V. “Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity.” Communications Biology (2020)

Sharma A, DasGupta R. “Tracking tumor evolution one-cell-at-a-time.” Molecular & Cellular Oncology (2019)

Sharma A. “Hiding in Plain Sight: Epigenetic Plasticity in Drug-Induced Tumor Evolution.” Epigenetics Insights (2019)

Sharma A, Cao EY, Kumar V, Zhang X, Leong HS, Wong AML, Ramakrishnan N, Hakimullah M, Teo HMV, Chong FT, Chia S, Thangavelu MT, Kwang XL, Gupta R, Clark JR, Periyasamy G, Iyer NG, DasGupta R. “Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy.” Nature Communications (2018)

Chia S, Low JL, Zhang X, Kwang XL, Chong FT, Sharma A, Bertrand D, Toh SY, Leong HS, Thangavelu MT, Hwang JSG, Lim KH, Skanthakumar T, Tan HK, Su Y, Choo SH, Hentze H, Tan IBH, Lezhava A, Tan P, Tan DSW, Periyasamy G, Koh JLY, Iyer NG, DasGupta R. “Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time.” Nature Communications (2017)

Hass MR, Liow HH, Chen X, Sharma A, Inoue YU, Inoue T, Reeb A, Martens A, Fulbright M, Raju S, Stevens M, Boyle S, Park JS, Weirauch MT, Brent MR, Kopan R. “SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers.” Molecular Cell (2015)